Exploring the processes of bacteria self-organization using mathematical modelling and experimental studies
Tuesday, June 15 at 04:15am (PDT)Tuesday, June 15 at 12:15pm (BST)Tuesday, June 15 08:15pm (KST)
Diane Peurichard (Inria Paris, France), Marie Doumic (Inria Paris, France)
Bacteria are ubiquitous unicellular organisms, whose biomass exceeds that of all other living organisms, and on which our survival is dependent. From a single organism, they quickly develop into complex and organized micro-colonies and biofilm structures, as a result of an interplay between various chemical and biological signaling as well as mechanical interactions. Understanding the mechanisms at play in this self-organization is not only essential for biological applications with medical and environmental perspectives (bioremediation of contaminants in soil, antibiotic resistance, food fermentation, filtration, antimicrobial action, wastewater treatment etc), but it also brings complex and more general theoretical questions about self-organization of interacting particle systems. The goal of this minisymposium is to bring together experts from different backgrounds to offer a state of the art view on the mechanisms at play in interacting particle systems, with a special focus on bacteria self-organization into micro-colonies. Through lab experiments, data driven modelling, theoretical and numerical analysis of mathematical models, this mini-symposium will emphasize the importance of interdisciplinarity in the study of biological systems, and illustrate how the synergy between biology and mathematics can lead to a new understanding of real systems, while bringing new challenges in both fields and enriching them greatly. The micro-colonies formation will be studied at different levels (individual or collective scales, deterministic or stochastic phenomena, etc) using different techniques (continuum/agent-based models, microscopy images, image processing tools, etc) with a particular focus on spatial organization and mechanical aspects.