The process of network translation corresponds a mass action system to a generalized mass action system with equivalent dynamics. Recent research has shown that, when the generalized chemical reaction network underlying the second network has desirable structure, such as weak reversibility and low deficiency, then we may use the network to establish properties of the steady state set and to explicitly construct a steady state parametrization. In this talk, we will extend this theory by introducing the method of 'splitting' networks. In a split network, we allow the original network to be partitioned into subnetworks, called 'slices', while imposing that the union of the subnetworks preserves the stoichiometry of the original network. We show that this process expands the scope of mass action systems whose steady states can be characterized by the method of network translation.

# Minisymposia-03

#### Monday, June 14 at 5:45pm (PDT)

Tuesday, June 15 at 01:45am (BST)

Tuesday, June 15 09:45am (KST)

# Minisymposia-03

##### MS03-CBBS:

Mathematics of Biochemical Reaction Networks

**Organized by:** Matthew Johnston (Lawrence Technological University, United States), Angelyn Lao (De La Salle University, Phillipines)

**Matthew Johnston***(Lawrence Technological University, United States)*

"Analyzing Steady States of Mass Action Systems through Network Splitting"**Editha Jose***(University of the Philippines Los Banos, Philippines)*

"Absolutely complex balanced power law kinetic systems"**Polly Yu***(University of Wisconsin-Madison, United States)*

"Conditions for stability of mass-action systems"**Bryan Hernandez***(University of the Philippines Diliman, Philippines)*

"Independent Decompositions of Chemical Reaction Networks and Some Applications"

##### MS03-CDEV:

Diverse quantitative approaches integrating data and modelling in development and medicine

**Organized by:** Adriana Dawes (Ohio State University, USA), Sungrim Seirin-Lee (Hiroshima University, Japan)

Note: this minisymposia has multiple sessions. The second session is **MS04-CDEV**.

**Sungrim Seirin-Lee***(Hiroshima University, Japan)*

"A one-line mathematical model that solved the mystery of urticaria"**Yoichiro Mori***(University of Pennsylvania, USA)*

"Mathematical Justification of Slender Body Theory"**Benjamin Walker***(University of Oxford, UK)*

"Hypothesis generation and hypothesis testing in spermatozoa"**Kang-Ling Liao***(University of Manitoba, Canada)*

"The role of CD200-CD200R in cancer immunotherapy"

##### MS03-DDMB:

Mathematics of Cryopreservation: from tissue preparation to freezing and ice formation

**Organized by:** Robyn Shuttleworth (University of Saskatchewan, Canada), James Benson (University of Saskatchewan, Canada)

**Adam Higgins***(Oregon State University, United States)*

"Rational design of less toxic cryoprotectant solutions for cryopreservation"**Ross Warner***(Oregon State University, United States)*

"A general strategy for modeling the distribution of cryoprotectants in tissues"**Fatemeh Amiri***(University of Saskatchewan, Canada)*

"Agent based tissue modeling of ice propagation"**Janet A. W. Elliott***(University of Alberta, Canada)*

"Thermodynamics of Cell and Tissue Cryopreservation"

##### MS03-ECOP:

The complex adaptive dynamics of honeybee societies

**Organized by:** Jun Chen (Arizona State University, USA), Yun Kang (Arizona State University, USA), Gabriela Zuloaga (Arizona State University, USA)

Note: this minisymposia has multiple sessions. The second session is **MS02-ECOP**.

**Adrian Fisher II***(Arizona State University, School of Life Sciences, United States)*

"A widely-used mito-toxic fungicide negatively affects honey bee (Apis mellifera) health"**Yixiang Wu***(Middle Tennessee State University, United States)*

"An Environmental Model of Honey Bee Colony Collapse Due to Pesticide Contamination"**Mary R Myerscough***(School of Mathematics and Statistics University of Sydney, Australia)*

"Modelling the role of temperature stress in honeybee colony collapse."**M. Gabriela Navas-Zuloaga***(School of Human Evolution and Social Change, Arizona State University, United States)*

"From Individual Phenotypes to Collective Behavior in Honeybee Foragers: A Mathematical Model"

##### MS03-EVOP:

Modeling and Simulations of COVID-19 impact and mitigation strategies

**Organized by:** Preeti Dubey and Christopher Hoover (Francis I. Proctor Foundation, UCSF, USA)

**Ranjit Upadhyay***(Indian Institute of Technology (ISM) Dhanbad, India)*

"Modeling the recent outbreak of COVID-19 in India and its Control strategies using NPIs and vaccination"**Christopher Hoover***(Francis I. Proctor Foundation, UCSF, USA)*

"Targeted allocation of testing and vaccination reduces transmission of SARS-CoV2 and improves health equity: An agent-based modeling study"**Morganne Igoe***(University of Tennessee, Knoxville, USA)*

"ZCTA-level Predictors of COVID-19 Hospitalization Risk in the St. Louis Area"**Preeti Dubey***(Francis I. Proctor Foundation, UCSF, USA)*

"Optimal vaccine prioritization for COVID-19 between high-risk and core group in California"

##### MS03-IMMU:

Collaboration and calibration: modelling with experimental and clinical data

**Organized by:** Adriana Zanca (The University of Melbourne, Australia), Jennifer Flegg (The University of Melbourne, Australia), Helen Byrne (University of Oxford, UK)

Note: this minisymposia has multiple sessions. The second session is **MS04-IMMU**.

**Alison Betts***(Applied BioMath, USA)*

"Modeling strategies for preclinical to clinical translation of T cell engager bispecific antibodies: using math to unravel counter intuitive dose responses"**Allison Lewis***(Lafayette College, USA)*

"Bayesian information-theoretic calibration of tumor models for informing effective scanning protocols"**Leili Shahriyari***(University of Massachusetts Amherst, USA)*

"A data-driven mathematical model of colon cancer"**Min Song***(University of Southern California, USA)*

"Quantitative analysis of endothelial sprouting mediated by FGF- and VEGF-induced MAPK and PI3K/Akt pathways"

##### MS03-MEPI:

Control Interventions for New, Rare and Neglected Infectious Diseases

**Organized by:** Stacey Smith? (The University of Ottawa, Canada) & Aurelio A. de los Reyes V (University of the Philippines Diliman)

**Hyojung Lee***(National Institute of Mathematical Sciences,, South Korea)*

" Effects of social distancing on transmission dynamics of COVID19 in Republic of Korea"**Stacey Smith?***(The University of Ottawa, Canada)*

"Modelling the daily risk of Ebola in the presence and absence of a potential vaccine"**May Anne Mata***(University of the Philippines Mindanao, Philippines)*

"Models of rabies incidence in Davao City, Philippines and their implications for policy makers"**Victoria May Mendoza***(University of the Philippines Diliman, Philippines)*

"A mathematical model and optimal control of Schistosomiasis in Agusan del Sur, Philippines"

##### MS03-MFBM:

Generalized Boolean network models and the concept of canalization

**Organized by:** Claus Kadelka (Iowa State University, United States)

Note: this minisymposia has multiple sessions. The second session is **MS02-MFBM**.

**Claus Kadelka***(Iowa State University, United States)*

"Collective canalization"**Elena Dimitrova***(California Polytechnic State University, United States)*

"Revealing the canalizing structure of Boolean functions — algorithms and applications"**Matthew Macauley***(Clemson University, United States)*

"Toggling independent sets as an asynchronous Boolean network"**Alan Veliz-Cuba***(University of Dayton, Ohio, United States)*

"Identification of control targets in Boolean networks via computational algebra"

##### MS03-MMPB:

Complex Fluids and Flows in Mathematical Biology

**Organized by:** Calina Copos (University of North Carolina at Chapel Hill, USA), Tony Gao (Michigan State University, USA), On Shun Pak (Santa Clara University, USA), Yuan-nan Young (New Jersey Institute of Technology, USA)

Note: this minisymposia has multiple sessions. The second session is **MS02-MMPB**.

**Tony Gao***(Michigan State University, USA)*

"Q-tensor model for undulatory swimming in a liquid crystal"**David Stein***(Simons Foundation, USA)*

"The many behaviors of deformable active droplets"**Herve Nganguia***(Indiana University of Pennsylvania, USA)*

"Swimming in a fluid pocket enclosed by a porous medium"**Anup Kanale***(University of Southern California, USA)*

"Flow-mediated instabilities in ciliary carpets"

##### MS03-NEUR:

Ionic Flow through Membrane Channels

**Organized by:** Peter Bates (Michigan State University), Weishi Liu (Mathematics, U. Kansas, USA), Mingji Zhang (Mathematics, New Mexico Tech., USA)

Note: this minisymposia has multiple sessions. The second session is **MS09-NEUR**.

**Bob Eisenberg***(Molecular Biophysics & Physiology, Rush University, USA)*

"Maxwell’s Core Equations Exact, Universal, and Scary"**Jianing Chen***(Mathematics, New Mexico Tech., USA)*

"Effects on zero-current ionic flows from ion sizes via PNP system with boundary layers"**Francisco Bezanilla***(Biochemistry and Molecular Biology and Institute for Biophysical Dynamics, University of Chicago and CINV, University of Valparaiso, Chile., USA)*

"Voltage sensors and ion channel opening"**Pei Liu***(Mathematics, U. Minnesota, USA)*

"Ion-dependent DNA Configuration in Bacteriophage Capsids"

##### MS03-ONCO:

Systems Biology Models of Tumor Metabolism

**Organized by:** Shubham Tripathi (Rice University, USA), Abhinav Achreja (University of Michigan, USA)

**Dongya Jia***(Laboratory of Integrative Cancer Immunology, National Cancer Institute, National Institutes of Health, USA)*

"Elucidating cancer catabolism and anabolism by coupling gene regulation with metabolic pathways"**Prahlad Ram***(The University of Texas MD Anderson Cancer Center, USA)*

"4D Ex-vivo CRISPR / CAS9 Whole-genome Screen to Identify Genes Regulating Early Lung Cancer Metastasis"**Andrew Raddatz***(The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, USA)*

"Kinetic Modeling of Redox Metabolism in Head and Neck Cancer"**Stacey Finley***(University of Southern California, USA)*

"Modeling tumor-stromal metabolic crosstalk in colorectal cancer"