Recent development in mathematical oncology in Asia and Australia
Tuesday, June 15 at 05:45pm (PDT)Wednesday, June 16 at 01:45am (BST)Wednesday, June 16 09:45am (KST)
Yangjin Kim (Konkuk University, Korea, Republic of), Eunjung Kim (Korea Institute of Science and Technology, Korea)
Cancer is a nonlinear and multiscale system that involves complex interactions between molecules, cells, and tissue. Genetic mutations occurring at a subcellular molecule level could drive functional changes at the cellular level, leading to tissue-level changes. Tissue-level properties produce selection pressure that governs the distribution and growth of cancer cells. In particular, the tumor microenvironments such as extracellular matrix, vascular bed, stromal cells are known to modulate tumour progression. Therefore, a thorough understanding of tumor microenvironment would provide a foundation to generate new strategies in therapeutic drug development. To understand this complex dynamical system, many mathematical models have been developed at a sub-cellular, tissue, and multiscale level. The main aim of this session is to discuss current stages and challenges in cancer modeling in Asia. Specific goals of the session include: (i) to analyze both computational and analytical solutions to various mathematical models of tumor growth and progression, (ii) to discuss how mathematical models can be used to support better clinical decisions, (iii) to present models that have improved our biochemical/biomechanical understanding of the fundamental mechanism that drives tumor progression, (iv) to discuss new treatment strategies guided by mathematical models.